Amm. Zumgottesberge et Jk. Mai, EXPRESSION OF THE CARBOHYDRATE EPITOPE 3-FUCOSYL-N-ACETYL-LACTOSAMINE(CD-15) IN THE ADULT GUINEA-PIG INNER-EAR, European journal of morphology, 33(2), 1995, pp. 129-135
The expression of the CD 15 (3-fucosyl-N-acetyl-lactosamin) epitope wa
s immunohistochemically studied on paraffin sections of adult guinea p
ig inner ears. Two regions of the inner ear expressed the epitope for
CD 15: the tectorial membrane of the cochlea and the endolymphatic sac
. The upper part of the main body of the tectorial membrane was deeply
stained. In the rugosal and distal part of the endolymphatic sac seve
ral unevenly distributed cells showed strong intra- and extracellular
localization of the CD 15 epitope. The CD 15 epitope is associated wit
h a transduction structure (tectorial membrane) and with a ''volume re
gulating'' compartment (endolymphatic sac) and may be involved in the
maintenance of the structural integrity of both.