Y. Kabasakal et al., SPINAL ABNORMALITIES SIMILAR TO ANKYLOSING-SPONDYLITIS IN A 58-YEAR-OLD WOMAN WITH OCHRONOSIS, Clinical rheumatology, 14(3), 1995, pp. 355-357
Ochronotic arthropathy (spondylosis or peripheral arthropathy) is a la
te complication of alkaptonuria. There is a tendency for HLA-B27 posit
ive patients with alkaptonuria to develop ochronotic spondylosis. A 58
-year-old white woman, presented with ochronotic spondylosis. She was
HLA-B27 positive. Her family history was positive for alkaptonuria. Oc
hronotic patients with HLA-B27 positivity develop spinal changes simil
ar to ankylosing spondilitis (AS).