The coexistence of polymyositis (PM) and primary biliary cirrhosis (PB
C) is rare; only nine cases have been described in English literature.
We report a case of a 46-year- old woman presenting with these two au
toimmune diseases. The diagnosis of PM was based on the symmetrical, p
roximal limb muscle weakness, elevated muscle enzymes and was confirme
d with the electromyography and muscle biopsy, The diagnosis of PBC wa
s based on the increased serum levels of alkaline phosphatase, gamma g
lutamyltransferase, IgM immunoglobulin, the presence of antimitochondr
ial antibodies and diagnostic liver biopsy.