Gs. Kelner et A. Zlotnik, CYTOKINE PRODUCTION PROFILE OF EARLY THYMOCYTES AND THE CHARACTERIZATION OF A NEW CLASS OF CHEMOKINE, Journal of leukocyte biology, 57(5), 1995, pp. 778-781
By using a variety of molecular techniques, we have characterized the
cytokine profile of pro-T cells. During this characterization we clone
d a novel cytokine that has chemotactic activities, We have designated
this cytokine lymphotactin. The structural analysis, chromosomal loca
tion, and biological properties of lymphotactin provide strong evidenc
e that this cytokine represents a new class of chemokine.