MICHAEL ADDITIONS OF 3,3-DIMETHYLACRYLAMIDES AND AMINES - SYNTHESIS OF THE GROWTH-HORMONE SECRETAGOGUE L-692,585

Authors
WELLS KM ROSSEN K ASKIN D HARTNER FW VOLANTE RP REIDER PJ
Citation
Km. Wells et al., MICHAEL ADDITIONS OF 3,3-DIMETHYLACRYLAMIDES AND AMINES - SYNTHESIS OF THE GROWTH-HORMONE SECRETAGOGUE L-692,585, Synthetic communications, 25(14), 1995, pp. 2197-2202
Citations number
8
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
25
Issue
14
Year of publication
1995
Pages
2197 - 2202
Database
ISI
SICI code
0039-7911(1995)25:14<2197:MAO3AA>2.0.ZU;2-G
Abstract
A highly efficient synthesis of the potent Human Growth Hormone Secret agogue L-692,585 1 via a Micheal addition with a 3,3-dimethyl acrylic acid derivative 7 and (R)-1-amino-2-propanol 2 is presented.