The urinary excretion of dimethylamine has been measured in 203 unrela
ted healthy volunteers (102 male) who maintained their normal diets. T
he results for female volunteers are the first reported in the literat
ure. The average daily output was 17.43 +/- 11.80 mg (mean +/- S.D.) (
21.21 +/- 14.78 male; 13.74 +/- 5.65 female) with values for the major
ity of the population lying within the 0.68-35.72 mg range. Four male
outliers excreted up to 109.2 mg; these large amounts of dimethylamine
were presumed to be of dietary origin. The literature pertaining to u
rinary levels of dimethylamine has been summarised and integrated with
the present observations.