Fine-needle aspiration biopsy (FNAB) and computed tomography (CT) or m
agnetic resonance imaging (MRI) are useful in the evaluation of saliva
ry gland tumors, but they are not essential for treatment planning in
every patient. The mainstay of therapy is a well-planned and carefully
executed surgical procedure which adequately excises the tumor. Disea
se-free survival is very likely in patients with early stage malignant
tumors. When treatment is delayed until the tumor is extensive (Stage
3,4), local recurrence and distant metastases are common and survival
rates are low. Adjunctive postoperative radiation therapy can enhance
locoregional control in the latter patients, but does not invariably
lead to better survival. No consistently effective chemotherapy agents
or combinations are presently available. Early diagnosis and consiste
nt, high quality treatment offer the best hope for improved survival.
(C) 1995 Wiley-Liss, Inc.