The prevalence of peripheral vascular disease in patients with coronar
y artery disease has been investigated in many different ways and depe
nds on the diagnostic methods and the definition of the atheroscleroti
c manifestations in the different vascular beds. In this study we used
the non-invasive methods digital volume pulse plethysmography and ank
le and toe blood pressure measurements to identify arterial abnormalit
ies in the lower limbs in 58 patients (49 males and 9 females; age 37-
72 years) examined with coronary angiography. The prevalence of periph
eral artery disease was 22%, in agreement with the results of most pre
vious investigations. There was a tendency towards increasing prevalen
ce of peripheral artery disease with more advanced coronary artery dis
ease: 14% of the patients with no or minimal coronary atheromotous les
ions, 18% of the patients with moderate coronary atheromotous lesions
and 32% of the patients with marked coronary atheromotous disease. For
this reason a non-invasive investigation of the peripheral arterial c
irculation should be included early in the clinical consideration of p
atients with chest pain or similar symptoms suggesting coronary heart
disease. Toe pressure measurement appears to be the mast appropriate t
echnique being rather simple in management and also in evaluation of r
esults.