We evaluated the microstructural characteristics of newly formed bone
tissue at the interface with cement. The bone-cement interfaces of the
femoral components of nine hip prostheses retrieved after loosening w
ere investigated by means of X-ray diffraction on microareas and micro
hardness. The bone far from the interface bf two stable prostheses was
used as a control. The newly formed bone adjacent to cement in the lo
osened prostheses showed a maturity degree lower than that of bone adj
acent to cement in stable prostheses. The lattice parameters of bone a
patite did not show significant variations as compared to the referenc
e values. Bone trabeculae at the interface with loosened prostheses of
ten showed an osteoid lining characterized by a strongly demineralized
lamellar and haversian structure. Radioopaque cement particles are so
metimes found in the trabecular bone tissue around the prosthesis. (C)
1995 John Wiley & Sons, Inc.