We present herein two unusual cases of multicentric liposarcoma which
highlight the problems associated with the management of this disease
entity. When the surgeon is confronted with multicentric liposarcomas,
it is necessary to define whether they are secondary tumors or indepe
ndently arising multicentric liposarcomas, since the latter situation
merits a more aggressive approach. Guidelines for this differentiation
are suggested in the discussion following the case reports. Surgery,
which is often multiple, remains the mainstay of treatment, although a
djuvant chemotherapy and radiotherapy are also usually required.