CHEMOENZYMATIC SYNTHESIS OF -O-(6'-O-ACYL-BETA-D-GALACTOPYRANOSYL)-SN-GLYCEROL

Authors
MORIMOTO T NAGATSU A MURAKAMI N SAKAKIBARA J
Citation
T. Morimoto et al., CHEMOENZYMATIC SYNTHESIS OF -O-(6'-O-ACYL-BETA-D-GALACTOPYRANOSYL)-SN-GLYCEROL, Tetrahedron, 51(23), 1995, pp. 6443-6450
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
51
Issue
23
Year of publication
1995
Pages
6443 - 6450
Database
ISI
SICI code
0040-4020(1995)51:23<6443:CSO->2.0.ZU;2-U
Abstract
Convenient synthesis of -O-(6'-O-acyl-beta-D-galactopyranosyl)-sn-glyc erol was studied. The lipase from Achromobacter sp, catalyzed acylatio n of 3-O-beta-D-galactopyranosyl-sn-glycerol, which contains two prima ry hydroxyl functions, proceeded regioselectively to furnish 1-O-acyl- 3-O-beta-D-galactopyranosyl-sn-glycerol.