UNILATERAL CEREBRAL CORTICAL AND BASAL GANGLIA ENHANCEMENT FOLLOWING OVERDOSAGE OF NONIONIC CONTRAST-MEDIA

A 69-year-old woman developed seizures after cerebral angiography imme diately preceded by coronary angiography. The preceding coronary angio graphy resulted in hyperconcentration, hyperosmolar loading, and overd osing of the nonionic contrast medium, A CT examination demonstrated g yriform enhancement throughout the left cortex and the left basal gang lia, Preloading with contrast material, as in this case, predisposes t o disruption of the blood-brain barrier during selective common caroti d or vertebral artery injection with nonionic contrast.