R. Enriquez et al., GRANULOMATOUS INTERSTITIAL NEPHRITIS ASSOCIATED WITH HYDROCHLOROTHIAZIDE AMILORIDE/, American journal of nephrology, 15(3), 1995, pp. 270-273
A 74-year-old woman developed acute renal failure and granulomatous in
terstitial nephritis associated with hydrochlorothiazide/amiloride. On
stopping the drug the renal function improved, but not significantly.
Around 20 months after prednisone administration, the renal function
had stabilized, with a moderate degree of renal insufficiency. The cas
e is discussed, and some aspects of acute interstitial nephritis induc
ed by diuretics are briefly reviewed.