Microgravity leads to a ''fluid shift'' towards the upper parts of the
body and, therefore, to a rise of the intraocular pressure, parabolic
flights have also demonstrated some rise of the intraocular pressure,
During the first German Spacelab mission D1, changes of the intraocul
ar pressure were investigated for the first time in space, The first p
ressure readings were obtained 44 min after entering microgravity and
showed a pressure rise of 20 to 25% compared to the baseline data, To
get earlier measurements in microgravity a fully automatic self-tonome
ter was developed which functioned independent of position and microgr
avity, It was used during an 8-d manned space mission in March 1992. M
easurements of the intraocular pressure have been performed 16 min aft
er reaching microgravity, The pressure readings revealed a 92% rise of
the intraocular pressure compared to the daytime-correlated baseline
data on Earth,