Hepatitis C Virus (HCV) is a RNA virus that lacks the retroviral prope
rties of surviving in infected hosts by integration into cellular DNA,
nevertheless it is capable to cause chronic infection and disease in
a considerable number of infected individuals (30-70% of cases). This
results in a worldwide prevalence of chronic HCV carriers similar to t
hose of hepatitis B virus carriers. We review and discuss here some of
the peculiar aspects of chronic HCV infection and associated disease.