LONG-TERM SEQUELAE OF PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME SECONDARY TO 5-FLUOROURACIL THERAPY

Authors
BANFIELD GK CRATE ID GRIFFITHS CL
Citation
Gk. Banfield et al., LONG-TERM SEQUELAE OF PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME SECONDARY TO 5-FLUOROURACIL THERAPY, Journal of the Royal Society of Medicine, 88(6), 1995, pp. 356-357
Citations number
5
Categorie Soggetti
Medicine, General & Internal
Journal title
Journal of the Royal Society of Medicine → ACNP
ISSN journal
01410768
Volume
88
Issue
6
Year of publication
1995
Pages
356 - 357
Database
ISI
SICI code
0141-0768(1995)88:6<356:LSOPES>2.0.ZU;2-D
Abstract
Palmar-Plantar erythrodyasesthesia syndrome has been reported as a tem porary complication of 5-fluorouracil therapy consisting of a debilita ting erythema and tenderness of the skin of hands and feet. The syndro me has previously been observed to respond rapidly to either temporary cessation of chemotherapy or pyridoxine with little residual disabili ty. We report a case which was characterized by persistent morbidity n ecessitating prolonged discontinuation of treatment.