ASYMMETRIC REDUCTION OF ORTHO-SUBSTITUTED BENZOPHENONES WITH B-CHLORODIISOPINOCAMPHEYLBORANE - A CONVENIENT SYNTHESIS OF ENANTIOMERICALLY ENRICHED BENZHYDROLS

Authors
SHIEH WC CANTRELL WR CARLSON JA
Citation
Wc. Shieh et al., ASYMMETRIC REDUCTION OF ORTHO-SUBSTITUTED BENZOPHENONES WITH B-CHLORODIISOPINOCAMPHEYLBORANE - A CONVENIENT SYNTHESIS OF ENANTIOMERICALLY ENRICHED BENZHYDROLS, Tetrahedron letters, 36(22), 1995, pp. 3797-3800
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
22
Year of publication
1995
Pages
3797 - 3800
Database
ISI
SICI code
0040-4039(1995)36:22<3797:AROOBW>2.0.ZU;2-H
Abstract
A very efficient synthesis of chiral benzhydrols from ortho-substitute d benzophenones is described which presumably utilizes a heteroatom-di rected, intramolecular asymmetric reduction of ketones with B-chlorodi isopinocampheylborane.