E. Schifferdecker et al., EXAMINATION OF PERIPHERAL NEUROPATHY IN T YPE-II DIABETICS - VALUE OFSENSORY THRESHOLD MEASUREMENT, Die medizinische Welt, 46(2), 1995, pp. 64-68
In 210 Type II diabetics (39-87 years old) pedal sensibility threshold
s for temperature, pain (PT) and vibration (VT) were measured, in 52 o
f these patients motoric (N. peroneaus) and sensory (N. suralis) nerve
conduction velocity (NCV) was determined. Cold thresholds (CT) were p
athologic in 54.3%, VT in 40.9%, warmth threshold in 23.3% and PT in 4
,3%. Only VT correlated significantly with diabetes duration (p <0.05)
. In 35 controls CT and VT were abnormal in 17.1 and 0%, respectively.
Motoric NCV was diminished in 20 of 52, sensory NCV in 22 of 52 patie
nts. With clinically advanced peripheral neuropathy (n = 33), CT and V
T were abnormal in 78.8 and 80%, respectively. In 14% of completely ev
aluated patients CT alone was pathologic, in 11% it was normal despite
other abnormal tests. Thus, CT is very sensitive even in elderly type
-II diabetics. However, its usefullness as early indicator of sensory
neuropathy remains still unclear because of the lack of specificity ob
served in this study.