FRUCTOSAMINE-LEVEL, GROWTH-HORMONE-LEVEL AND SOMATOMEDIN C-LEVEL IN UMBILICAL-CORD BLOOD IN CORRELATION TO BIRTH-WEIGHT

In 81 pregnancies (40 primipara/41 multipara) with inconspicuous histo ry, postpartal venous blood concentrations of fructosamine, growth hor mone, and somatomedin-C in the umbilical cord were measured to determi ne a possible correlation with the birth weight and height (before del ivery of the placenta). This correlation was statistically proved by l inear regression. The serum levels in the umbilical cord blood were in the case of fructosamine 170.4+/-22.5 mcmol/l, STH 24.1+/-18.1 ng/ml and somatomedin-C 0.4+/-0.12 U/ml. A significant correlation was found for somatomedin-C (=IFC I) concentration and weight of the newborn an d weight of placenta (p<0.05). Further somatomedin C concentration dep ends on the gender (39 females, 42 males) with a significance of p <0. 043.There was no significance between fructosamine. STH-concentration and birth weight and height. It seems that the evaluation of somatomed in-C could be a useful diagnostic parameter for fetal and paediatric g rowth deficits.