HEPATITIS-B VIRUS-INFECTION ON A TROPICAL ISLAND - SOCIODEMOGRAPHIC AND GEOGRAPHIC RISK-FACTORS IN GUADELOUPE

A seroepidemiologic study on a cross-sectional sample of blood donors was carried out in Guadeloupe, a French West Indies island, to estimat e the prevalence of hepatitis B virus (HBV) markers, and to investigat e the influence of age, socioeconomic, and geographic factors on prior HBV infection. Blood specimens and sociodemographic data were collect ed in 1989 from 2,339 blood donors residing on the island. A total of 73 (3.1%) of 2,339 were found to be HBV surface antigen carriers, and 518 (22.1%) were positive for antibody to HBV core antigen. Among them , 61 were positive for both markers and consequently 530 persons (22.7 %) were considered to have evidence of prior HBV infection. Multivaria te logistic regression analyses identified age and low socioprofession al status as being related to HBV infection, as in many endemic areas. In addition, some major geographic risk factors were highlighted, ref lecting a strongly hyperendemic situation in specific areas and the po tential influence of horizontal transmission or unknown environmental factors on these particular populations.