DETECTION OF 72-75-KD AND 123-KD FRACTIONS OF LEISHMANIA ANTIGEN IN URINE OF PATIENTS WITH VISCERAL LEISHMANIASIS - SHORT REPORT

Citation
M. Decolmenares et al., DETECTION OF 72-75-KD AND 123-KD FRACTIONS OF LEISHMANIA ANTIGEN IN URINE OF PATIENTS WITH VISCERAL LEISHMANIASIS - SHORT REPORT, The American journal of tropical medicine and hygiene, 52(5), 1995, pp. 427-428
Citations number
3
Categorie Soggetti
Public, Environmental & Occupation Heath","Tropical Medicine
ISSN journal
00029637
Volume
52
Issue
5
Year of publication
1995
Pages
427 - 428
Database
ISI
SICI code
0002-9637(1995)52:5<427:DO7A1F>2.0.ZU;2-A
Abstract
Two polypeptide fractions of 72-75 kD were detected in the urine of 14 of 15 patients with visceral leishmaniasis (VL) and another fraction of 123 kD was found in 10 of the 15 patients by using a Western blot t echnique. None of these fractions was detected in the urine of 20 cont rols. These results suggest that antigen detection in urine could be a powerful, noninvasive method for VL diagnosis.