CUCURBITACIN GLYCOSIDES FROM CABECA-DE-NEGRO

Five cucurbitacin glycosides named cabenosides D-L were isolated from 'Cabeca-de-negro', the roots of Caput nigri. Among them, the structure s of cabenosides D-H were elucidated as 10 alpha-cucurbit-5-en-11-oxo- 3 beta,24R,25-triol-3-O-beta-D-glucopyranoside, 10 alpha-cucurbit-5-en -24-oxo-3 beta,11 alpha,25-triol-25-O-beta n-D-glucopyranosyl, [3,O-be ta-D-glucopyranoside, eta-D-glucopyranosyl-(1-2)-beta-D-glucopyranosid e, eta-D-glucopyranosyl-(1-6)-beta-D-glucopyranoside] and 10 alpha-cuc urbit-5-en-11,24-dioxo-3 beta,25-diol-25-O-beta-D-glucopyranosyl, beta -D-glucopyranosyl(1-6)-beta-D-glucopyranoside, respectively, on the ba sis of chemical and spectral evidence.