Sg. Swisher et al., CHANGES IN THE SURGICAL-MANAGEMENT OF ESOPHAGEAL CANCER FROM 1970 TO 1993, The American journal of surgery, 169(6), 1995, pp. 609-614
PURPOSE: To evaluate the changes since 1970 in the management and outc
ome of esophageal resection for cancer. METHODS: The records of all 31
6 patients who underwent esophageal resection for cancer at University
of California Los Angeles Medical Center during the years 1970 to 199
3 were reviewed, RESULTS: When records from 1984 to 1993 were compared
to those from 1970 to 1983, significant decreases were seen in operat
ive mortality (10% to 3%, P <0.01), morbidity (72% to 60%, P <0.05), a
nastomotic leaks (12% to 5%, P <0.03), and reoperations (20% to 8%, P
<0.003), Time spent in hospital and in intensive care decreased 40%. T
hese improvements in short-term outcome were most evident in patients
with disease in later stages. The 5-year survival rate increased (12%
to 21%, P <0.01), A greater percentage of tumors presented in early st
ages (21% versus 37%). CONCLUSIONS: Short-term outcome of surgical res
ection for esophageal carcinoma improved between 1970 and 1993, in par
t because of changes in perioperative and surgical management, Long-te
rm survival improved, probably due to earlier detection of tumors.