The list of detected refractory-element (RE) species in IRC10216 is no
w large enough to try to assess their chemistry, and the fraction of e
ach that escapes in gas phase to the ISM. The former may tell us how g
rains are formed, the latter whether mass-loss from evolved stars is i
mportant in determining interstellar elemental depletions as distinct
from accretion processes in the ISM. We expect that much of the Si che
mistry is now understood and about 25% of Si escapes as a gas. Other R
Es are less well understood but most should be more volatile than Si.
For many of the REs, O-rich CSEs should behave similarly to C-rich one
s.