C. Madden et al., HIGH-YIELD SELECTION CRITERIA FOR CRANIAL COMPUTED-TOMOGRAPHY AFTER ACUTE TRAUMA, Academic emergency medicine, 2(4), 1995, pp. 248-253
Objective: To develop and prospectively evaluate criteria for selectin
g head-injured patients requiring cranial CT. Methods: A two-phased pr
ospective observational study design was implemented at a university E
D. Physicians completed a form with 51 variables for 540 patients in P
hase I. Ten high-yield variables were identified and prospectively tes
ted on 273 patients in Phase II. Prediction rule performance for ident
ification of patients with abnormal CT scans was determined. Results:
The combined criteria had a sensitivity of 97% for CT-scan abnormaliti
es in Phase I; sensitivity was 96% in Phase II. Negative predictive va
lues were 97% and 94%, respectively. Prevalence of disease in Phase I
was 17%; prevalence in Phase II was 16%. Had the Phase I criteria been
implemented during Phase II, 43 of 273 patients (16%) would not have
been scanned, including two patients with positive results who did not
require operative intervention. Conclusions: Fifty-one clinical varia
bles from head-injured patients were narrowed to ten of statistical si
gnificance and consistent interpretation for prospective evaluation. P
atients with none of these criteria were found to be at low risk of ha
ving sustained significant head injury.