SYNTHESIS AND CONFIGURATIONAL DETERMINATI ON OF 11-CHLOROARTEMISININ

Authors
LU DW LI Y
Citation
Dw. Lu et Y. Li, SYNTHESIS AND CONFIGURATIONAL DETERMINATI ON OF 11-CHLOROARTEMISININ, Gaodeng xuexiao huaxue xuebao, 16(2), 1995, pp. 237-238
Citations number
7
Categorie Soggetti
Chemistry
Journal title
Gaodeng xuexiao huaxue xuebao → ACNP
ISSN journal
02510790
Volume
16
Issue
2
Year of publication
1995
Pages
237 - 238
Database
ISI
SICI code
0251-0790(1995)16:2<237:SACDOO>2.0.ZU;2-R
Abstract
11-Chloroartemisinin, a new derivative of artemisinin, was prepared by treating 11 alpha-hydroxyartemisinin with SOCl2/Pyr with retention of configuration. 11-Chloro atom having alpha orientation was determinat ed by NMR technique and molecular mechanic calculation.