Kj. Cong et al., CALCIUM SUPPLEMENTATION DURING PREGNANCY FOR REDUCING PREGNANCY-INDUCED HYPERTENSION, Chinese medical journal, 108(1), 1995, pp. 57-59
Pregnancy induced hypertension (PIH) is a common complication in pregn
ancy and prenatal stage. Because the direct and indirect relationship
between low calcium intake and many diseases, such as rachitis, young
age myopia and hypertension, calcium supplementation has been a hot to
pic among nutritionists, Randomized trials of calcium supplementation
during pregnancy were conducted in 212 healthy primipara. They were di
vided into 4 groups and pave 120mg, 240mg, Ig or 2g of calcium daily f
rom 20 to 28wks of gestation up to delivery respectively. As a result,
the incidence of PIH was 8.9%, 7.5%, 8% and 4% respectively in these
groups, The control group (106 pregnant women) who did not receive cal
cium gave an incidence of 18%. Supplementation of 2g of calcium daily
showed significant resutls in lowering the incidence of PM (P<0.05) wi
thout any adverse effects. In 1992 calcium supplementation was widely
used in antenatal clinic. 200 cases with intake of 2g calcium were com
pared with corresponding non-calcium supplementation cases, and the in
cidence of PIH was 7.5% and 16.5% (P< 0.005) respectively. Mediating p
arathyroid hormone and renin activity are thought to be the effect of
calcium on decreasing the incidence of PIH,