METABOLIC EFFECTS OF INTERMITTENT EXERCIS E IN PATIENTS WITH PERIPHERAL ARTERIAL OCCLUSIVE DISEASE STAGE-II

During intermittent exercise lasting six minutes with two minutes' res t the fluctuations in arterial and venous blood of lactate, pyruvate a nd blood gases as well as changes in the lactate pyruvate ratio were s tudied in eleven patients with intermittent claudication. There were s ignificant differences of O-2-extraction during intermittent exercise. The level of arterial lactate did not vary significantly. The highest venous lactate was found during the rest period. Significant differen ces in venous lactate, pyruvate and la:tate pyruvate ratio were found between the first and second exercise periods. It is assumed that the rate of glycolysis is reduced during intermittent exercise.