AMPHOTERICIN-B FOLLOWED BY ITRACONAZOLE IN THE TREATMENT OF DISSEMINATED FUNGAL-INFECTIONS IN NEUTROPENIC PATIENTS

Citation
M. Nucci et al., AMPHOTERICIN-B FOLLOWED BY ITRACONAZOLE IN THE TREATMENT OF DISSEMINATED FUNGAL-INFECTIONS IN NEUTROPENIC PATIENTS, Mycoses, 37(11-12), 1994, pp. 433-437
Citations number
18
Categorie Soggetti
Dermatology & Venereal Diseases",Mycology
Journal title
ISSN journal
09337407
Volume
37
Issue
11-12
Year of publication
1994
Pages
433 - 437
Database
ISI
SICI code
0933-7407(1994)37:11-12<433:AFBIIT>2.0.ZU;2-D
Abstract
The role of the new triazoles in the treatment of disseminated fungal infections in neutropenic patients is at present under scrutiny. Six n eutropenic patients with disseminated fungal infections were treated w ith amphotericin B during neutropenia and itraconazole after bone marr ow recovery. There were three pulmonary aspergillomas, one Aspergillus fumigatus sinusitis, one Fusarium-mycosis and one disseminated candid osis. Four patients were cured of the infection. This approach seems t o be safe and effective in the treatment of disseminated fungal infect ions in neutropenic patients, with the advantages of low side-effects and the possibility of early discharge from hospital.