STUDIES ON FLUORESCENT PROPERTY OF DEGRAD ATION PRODUCT OF CEPHALEXINAND ITS ANALYTICAL APPLICATION

Authors
Citation
Xw. He et al., STUDIES ON FLUORESCENT PROPERTY OF DEGRAD ATION PRODUCT OF CEPHALEXINAND ITS ANALYTICAL APPLICATION, Gaodeng xuexiao huaxue xuebao, 16(1), 1995, pp. 26-30
Citations number
4
Categorie Soggetti
Chemistry
ISSN journal
02510790
Volume
16
Issue
1
Year of publication
1995
Pages
26 - 30
Database
ISI
SICI code
0251-0790(1995)16:1<26:SOFPOD>2.0.ZU;2-H
Abstract
In this paper, the degradation reactions of cephalexin in acid and alk ali media are described in detail, and the corresponding fluorometric methods of cephalexin are presented by producing its stable fluorescen t products, The linear ranges are 0.50-100 ng/mL (acid degradation) an d 2.0-70 ng/mL (alkali degradation), respectively, The fluorometry wit h acid degradation has more advantages of analytical precission and is more accuracy than that with alkali degradation, which has been used for the determination of trace cephalexin in human serum and urine wit h satisfactory results.