Trauma and compression along the course of the median, ulnar or radial
nerve from the brachial plexus to the fingers may cause pain, weaknes
s, numbness or tingling of the upper extremity. Diabetes, smoking, alc
ohol consumption, rheumatoid arthritis and hypothyroidism are risk fac
tors for nerve entrapment, although these disorders typically produce
bilateral symptoms. Carpal tunnel syndrome, the most common nerve entr
apment condition, results from median nerve compression at the wrist.
The diagnosis is suggested by decreased pain sensation and numbness in
the thumb and index and middle fingers; symptoms are reproduced by wr
ist hyperflexion and median nerve percussion. Volar splinting and ster
oid injection often ameliorate symptoms. Decreased sensation of the li
ttle finger and the ulnar aspect of the ring finger, along with intrin
sic muscle weakness, may be caused by cervical radiculopathy, thoracic
outlet syndrome or compression of the ulnar nerve above the elbow (cu
bital tunnel syndrome) or at the wrist (ulnar tunnel syndrome). Electr
omyography and radiography may help differentiate these conditions. Ra
dial tunnel syndrome occasionally accompanies inflammation of the comm
on wrist extensors and lateral epicondylitis (''tennis elbow''). A rad
ial nerve block can help exclude concomitant radial tunnel syndrome in
patients with symptoms of lateral epicondylitis.