Pm. Kramme et al., TEMPORAL STABILITY OF THE VIRUS LOAD OF CATTLE INFECTED WITH BOVINE LEUKEMIA-VIRUS, Veterinary immunology and immunopathology, 45(3-4), 1995, pp. 347-354
The relative virus load of bovine leukemia virus (BLV) infected cattle
was measured by an immunoperoxidase infectivity assay (IPIA), and by
immunoperoxidase staining of cultured leukocytes using a monoclonal an
tibody to the capsid protein (p24) of BLV. The results of paired sampl
e data taken at different time points spanning 2-3 years show that BLV
-infected cattle are stable regarding the amount of BLV produced by th
eir peripheral blood mononuclear cells (PBMCs). Spearman's Rank Correl
ation demonstrated significant relationships between data from individ
ual cattle taken at four different time points. In addition, this stud
y documents the large range of variation in the virus load of individu
al cattle.