THE ONTOGENY OF BRONCHIAL REACTIVITY

Authors
FAYON M BENJEBRIA A ELLEAU C DEMARQUEZ JL MARTHAN R
Citation
M. Fayon et al., THE ONTOGENY OF BRONCHIAL REACTIVITY, Annales de pediatrie, 42(3), 1995, pp. 170-175
Citations number
NO
Categorie Soggetti
Pediatrics
Journal title
Annales de pediatrie → ACNP
ISSN journal
00662097
Volume
42
Issue
3
Year of publication
1995
Pages
170 - 175
Database
ISI
SICI code
0066-2097(1995)42:3<170:TOOBR>2.0.ZU;2-R
Abstract
This article reviews current knowledge on the mechanisms involved in t he maturation of bronchial contractility in animal models and humans. Extrapolation of animal data to humans is risky. Results of an in vitr o study in human neonates are reported. beta(2)-adrenoceptor agonists and cholinergic agents were effective in relieving early bronchospasm in mechanically-ventilated premature infants. Controlled studies are n eeded to determine whether these medications affect the subsequent occ urrence of bronchial hyperreactivity in these patients.