A NOVEL TAQI DQA RFLP ASSOCIATED WITH HLA-DR9,DQ9 (DQA1-ASTERISK-0302)/

Authors
VILCHES C DEPABLO R SOLIS R MARTIN R HERRERO MJ MORENO ME KREISLER M
Citation
C. Vilches et al., A NOVEL TAQI DQA RFLP ASSOCIATED WITH HLA-DR9,DQ9 (DQA1-ASTERISK-0302)/, European journal of immunogenetics, 22(3), 1995, pp. 261-264
Citations number
7
Categorie Soggetti
Immunology,"Genetics & Heredity
Journal title
European journal of immunogenetics → ACNP
ISSN journal
09607420
Volume
22
Issue
3
Year of publication
1995
Pages
261 - 264
Database
ISI
SICI code
0960-7420(1995)22:3<261:ANTDRA>2.0.ZU;2-9
Abstract
A new TaqI/DQA restriction fragment length polymorphism (RFLP) has bee n found in two Spanish Caucasoid individuals. The novel polymorphic fr agment has a relative mobility of 4.2 kb and is associated with an HLA -A2,Cw1401,B51,DR9,DR53,DQ9 haplotype. Nucleotide sequence analysis i ndicates that individuals showing this RFLP pattern do not carry a new DQA1 allele, but that (DQA10302) commonly observed in DR9,DQ9 haplot ypes. The new RFLP seems to be a locally restricted marker of uncertai n origin.