PREPARATION OF HOMOLOGOUS PYRAZOLONEDICARBOXYLATES

Authors
MAKAREVIC J SKARIC V
Citation
J. Makarevic et V. Skaric, PREPARATION OF HOMOLOGOUS PYRAZOLONEDICARBOXYLATES, Heterocycles, 41(6), 1995, pp. 1207-1218
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
41
Issue
6
Year of publication
1995
Pages
1207 - 1218
Database
ISI
SICI code
0385-5414(1995)41:6<1207:POHP>2.0.ZU;2-R
Abstract
Homologous disodium pyrazolonedicarboxylates (8, 16f and 16g) as possi ble protectors of cis-DDP induced nephrotoxicity, have been prepared b y the reaction of hydrazine with di-t-butyl ethyl beta-keto triesters (5b, 13b and 13c) and subsequent hydrolysis of formed di-t-butyl pyraz olonedicarboxylates (6b, 14b and 14c).