Setting: A retrospective study of tuberculosis notifications in Englan
d and Wales published by the Office of Population Censuses and Surveys
. Objective: To analyse the rise in tuberculosis notifications in Engl
and and Wales by different sub groups over the time period 1982-91. De
sign: The average annual percentage change in tuberculosis notificatio
n rates (per 100 000) for the groups were analysed by age, sex, standa
rd region and disease site. Results: The average annual increase in tu
berculosis notifications from 1987-91 in females was +2.55 (95% confid
ence interval [CI] 0.5-4.7); males showed no significant change (-0.6%
, 95% CI: -2.9 to +2.7). The increase was greater in younger subjects:
3.2% in females aged 25-44 (95% CI 0.9-5.5) and 4.3% in males aged 15
-24 (95% CI 1.7-6.9). Only three standard regions showed an increase:
the South East, the West Midlands, Yorkshire and Humberside. This incr
ease was significant only in females from the South East, and was pred
ominantly in non-respiratory tuberculosis. Conclusion: The rise in tub
erculosis notification rates from 1987-91 has been predominantly in fe
males, in those under 65, has occurred in 3 regions, and predominantly
in non-respiratory tuberculosis. The analysis highlights some of the
inadequacies of the present notification system for tuberculosis.