FARNESYL DIPHOSPHATE SYNTHASE REACTIONS WITH DIMETHYLALLYL DIPHOSPHATE ANALOGS HAVING OXYGEN-ATOMS IN THEIR CHAINS

Authors
MAKI Y KURIHARA M ENDO T ABIKO M SAITO K WATANABE G OGURA K
Citation
Y. Maki et al., FARNESYL DIPHOSPHATE SYNTHASE REACTIONS WITH DIMETHYLALLYL DIPHOSPHATE ANALOGS HAVING OXYGEN-ATOMS IN THEIR CHAINS, Chemistry Letters, (5), 1995, pp. 389-390
Citations number
13
Categorie Soggetti
Chemistry
Journal title
Chemistry Letters → ACNP
ISSN journal
03667022
Issue
5
Year of publication
1995
Pages
389 - 390
Database
ISI
SICI code
0366-7022(1995):5<389:FDSRWD>2.0.ZU;2-9
Abstract
Six dimethylallyl diphosphate analogues having oxygen atoms in their a lkyl chains were found to act as substrate in the reaction catalyzed b y pig liver farnesyl diphosphate synthase to give geranyl diphosphate analogues or farnesyl diphosphate analogues. The number of IPP incorpo rated into the product depended on not only the length of the chain bu t also its hydrophobicity.