IMMUNE-MEDIATED MYELOPATHY AFTER ALLOGENEIC MARROW TRANSPLANTATION

Authors
OPENSHAW H SLATKIN NE PARKER PM FORMAN SJ
Citation
H. Openshaw et al., IMMUNE-MEDIATED MYELOPATHY AFTER ALLOGENEIC MARROW TRANSPLANTATION, Bone marrow transplantation, 15(4), 1995, pp. 633-636
Citations number
10
Categorie Soggetti
Hematology,Oncology,Immunology,Transplantation
Journal title
Bone marrow transplantation → ACNP
ISSN journal
02683369
Volume
15
Issue
4
Year of publication
1995
Pages
633 - 636
Database
ISI
SICI code
0268-3369(1995)15:4<633:IMAAMT>2.0.ZU;2-8
Abstract
We describe two patients who developed myelopathy 15 and 27 months aft er allogeneic marrow transplantation. Exacerbations of the myelopathy occurred, with the development of optic neuropathy in one patient when corticosteroid therapy was tapered, The other patient had two exacerb ations, 28 months and 40 months after transplantation, both of which r esolved with plasmapheresis. These case reports suggest that immune-me diated disease after transplantation can affect the central nervous sy stem.