INTERACTION OF DNA WITH ACTINOCYL-BIS-BITHIAZOLE

The DNA complexes with actinocyl-bis-bithiazole were examined by spect rophotometry, viscosimetry, and dynamic flow birefringence. It was sho wn that at a low extent of binding actinocyl-bis-bithiazole interacts with DNA by bisintercalation via its bithiazole fragments. The phenoxa zone chromophore functions as a linker connecting the intercalating fr agments. At a higher binding extent, external binding is observed.