MOLECULAR CHARACTERIZATION OF THE OXA-7 BETA-LACTAMASE GENE

Citation
E. Scoulica et al., MOLECULAR CHARACTERIZATION OF THE OXA-7 BETA-LACTAMASE GENE, Antimicrobial agents and chemotherapy, 39(6), 1995, pp. 1379-1382
Citations number
24
Categorie Soggetti
Pharmacology & Pharmacy",Microbiology
ISSN journal
00664804
Volume
39
Issue
6
Year of publication
1995
Pages
1379 - 1382
Database
ISI
SICI code
0066-4804(1995)39:6<1379:MCOTOB>2.0.ZU;2-F
Abstract
The OXA-7 gene, which encodes an oxacillinase, was cloned from plasmid pMG202 of Escherichia coli isolate 7181 (A. A. Medeiros, M. Cohenford , and G. A. Jacoby, Antimicrob. Agents Chemother. 27:715-719, 1985) an d sequenced. The nucleotide sequence of the OXA-7 gene was closely rel ated to that of the OXA-10 (PSE-2) gene, with a derived amino acid seq uence of the OXA-7 enzyme shelving greater than 95% homology with thos e of OXA-10 and OXA-11.