The OXA-7 gene, which encodes an oxacillinase, was cloned from plasmid
pMG202 of Escherichia coli isolate 7181 (A. A. Medeiros, M. Cohenford
, and G. A. Jacoby, Antimicrob. Agents Chemother. 27:715-719, 1985) an
d sequenced. The nucleotide sequence of the OXA-7 gene was closely rel
ated to that of the OXA-10 (PSE-2) gene, with a derived amino acid seq
uence of the OXA-7 enzyme shelving greater than 95% homology with thos
e of OXA-10 and OXA-11.