Lymphomatoid granulomatosis is a disease affecting the pulmonary syste
m which is not usually associated with involvement of the central nerv
ous system (CNS). Isolated central nervous system involvement is rare.
This case, of a 65-year-old male, was notable not only as a case of l
ymphomatoid granulomatosis with isolated central nervous system involv
ement, but also with the unusual occurrence of a temporal pattern of r
egression and recrudescence of individual lesions not related to thera
peutic intervention.