SYNTHESIS OF NOVEL PHOSPHORAMIDITE DERIVATIVES BEARING PYRENYL AND DANSYL GROUPS

Authors
BURMEISTER J AZZAWI A VONKIEDROWSKI G
Citation
J. Burmeister et al., SYNTHESIS OF NOVEL PHOSPHORAMIDITE DERIVATIVES BEARING PYRENYL AND DANSYL GROUPS, Tetrahedron letters, 36(21), 1995, pp. 3667-3668
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
21
Year of publication
1995
Pages
3667 - 3668
Database
ISI
SICI code
0040-4039(1995)36:21<3667:SONPDB>2.0.ZU;2-6
Abstract
The synthesis of novel phosphoramidites is reported starting with the readily available 4-(1-pyrenyl)-butanol or 5-(dimethylamino)naphthalen e-1-sulfonic acid chloride, respectively. Both amidites can be used on the DNA synthesizer to prepare 5'- or internally labeled oligonucleot ides without an acyl amide linkage to the fluorescent dye.