In a model designed for experimental cryoablation of the His bundle in
swine, a study that required multiple and follow-up cardiac catheteri
zations, femoral percutaneous cannulations were successfully performed
in 14 of 15 swine: 6/6 Yucatan miniature, 5/6 Hanford miniature, and
3/3 Yorkshire farm pigs, weight range 15-50 kg. A follow-up cardiac ca
theterization was performed in 10 of these animals: 5 Hanford and 5 Yu
catan. Femoral percutaneous cannulation was successful in 6. A cutdown
approach was successful in the remaining 4 after failed attempts at p
ercutaneous vascular access. The results show that percutaneous femora
l cardiac catheterization is a feasible and practical technique for ca
rdiovascular studies in swine, especially those thar require multiple
and serial catheterizations.