EFFECTS OF STORAGE-CONDITIONS AND COMPOSI TION OF VIRUS SUSPENSIONS ON LIPID-PEROXIDATION OF THE VIRUS ENVELOPES AND INACTIVATION OF INFLUENZA-VIRUS

Authors
PORYVAYEV VD ZYKOVA NA
Citation
Vd. Poryvayev et Na. Zykova, EFFECTS OF STORAGE-CONDITIONS AND COMPOSI TION OF VIRUS SUSPENSIONS ON LIPID-PEROXIDATION OF THE VIRUS ENVELOPES AND INACTIVATION OF INFLUENZA-VIRUS, Voprosy virusologii, 40(2), 1995, pp. 62-65
Citations number
NO
Categorie Soggetti
Virology
Journal title
Voprosy virusologii → ACNP
ISSN journal
05074088
Volume
40
Issue
2
Year of publication
1995
Pages
62 - 65
Database
ISI
SICI code
0507-4088(1995)40:2<62:EOSACT>2.0.ZU;2-V
Abstract
Lipid peroxidation (LPO) develops in the virus envelopes in the course of storage of influenza virus suspensions. It is registered by fluore scent methods by the time course of intermediate products (short-chain dialdehydes) and final products of LPO (fluorescent pigment), this be ing characteristic of an autocatalytic process. The conformity of the basic regularities of LPO and virus inactivation in samples differing by the storage conditions, concentrations of virions and antioxidants (alpha-tocopherol acetate and phenosan) permits us to consider LPO as an important mechanism of enveloped virus inactivation during storage.