Vd. Poryvayev et Na. Zykova, EFFECTS OF STORAGE-CONDITIONS AND COMPOSI TION OF VIRUS SUSPENSIONS ON LIPID-PEROXIDATION OF THE VIRUS ENVELOPES AND INACTIVATION OF INFLUENZA-VIRUS, Voprosy virusologii, 40(2), 1995, pp. 62-65
Lipid peroxidation (LPO) develops in the virus envelopes in the course
of storage of influenza virus suspensions. It is registered by fluore
scent methods by the time course of intermediate products (short-chain
dialdehydes) and final products of LPO (fluorescent pigment), this be
ing characteristic of an autocatalytic process. The conformity of the
basic regularities of LPO and virus inactivation in samples differing
by the storage conditions, concentrations of virions and antioxidants
(alpha-tocopherol acetate and phenosan) permits us to consider LPO as
an important mechanism of enveloped virus inactivation during storage.