INTRAACCUMBENS DELTA(1)-OPIOID AGONIST, PCL-DPDPE, DIFFERENTIALLY AFFECTS PATTERNS OF LOCOMOTOR-ACTIVITY

Authors
MEYER ME MCLAURIN BI MEYER ME
Citation
Me. Meyer et al., INTRAACCUMBENS DELTA(1)-OPIOID AGONIST, PCL-DPDPE, DIFFERENTIALLY AFFECTS PATTERNS OF LOCOMOTOR-ACTIVITY, Pharmacology, biochemistry and behavior, 51(2-3), 1995, pp. 359-362
Citations number
15
Categorie Soggetti
Pharmacology & Pharmacy","Pharmacology & Pharmacy
Journal title
Pharmacology, biochemistry and behavior → ACNP
ISSN journal
00913057
Volume
51
Issue
2-3
Year of publication
1995
Pages
359 - 362
Database
ISI
SICI code
0091-3057(1995)51:2-3<359:IDAPDA>2.0.ZU;2-#
Abstract
The effects of bilateral microinjections of a new potent and highly se lective delta-opioid receptor agonist pCl-DPDPE (0.00, 0.1, 1.0, or 2. 5 mu g/side) were tested in rats for 60 min in activity monitors. The durations of horizontal movement time, rearing time, and stereotypy ti me were measured during six consecutive 10-min time blocks. The pCl-DP DPE resulted in short-lived biphasic effects of attenuation followed b y potentiation for the three measures. These data in part replicate th e behavioral effects of other delta-opioid receptor agonists.