Fj. Fowler et al., EFFECT OF RADICAL PROSTATECTOMY FOR PROSTATE-CANCER ON PATIENT QUALITY-OF-LIFE - RESULTS FROM A MEDICARE SURVEY, Urology, 45(6), 1995, pp. 1007-1013
Objectives. To assess patient responses to radical prostatectomy and i
ts effects. Methods. A national sample was taken of 1072 Medicare pati
ents who underwent radical prostatectomy for prostate cancer (1988 thr
ough 1990) by mail, telephone, and personal interviews. The effects of
the surgery and its complications On these patients' lives were studi
ed through: (1) patient ratings of the extent to which sexual and urin
ary dysfunctions were ''problems'' in their lives; (2) two general mea
sures of quality of life, the Mental Health Index and the General Heal
th Index; (3) patient reports of how they felt about the results of tr
eatment and whether they would choose surgery again. Results. On avera
ge, dripping urine, particularly to the point where subjects were wear
ing pads, had a more significant effect on patients than loss of sexua
l function; incontinence had significant adverse effects on the measur
es of quality of life and self-reported results of surgery. Overall, p
ostsurgical patients scored comparatively high on the quality of life
measures (similar to a cohort of patients with benigh prostatic hyperp
lasia who had undergone transurethral resection of the prostate), repo
rted feeling positive about the results (81%), and would choose surgic
al treatment again (89%). Nonetheless, there was variability in patien
t response to the effects of surgery. Conclusions. The results demonst
rate the ability of many Medicare patients to adapt to adverse outcome
s, such as loss of sexual function and incontinence. They also provide
evidence of the variability of individual patients' responses to surg
ical results and reinforce the importance of individualized decision m
aking for patients facing a decision about radical prostatectomy for p
rostate cancer.