The nature of hazard identification and risk assessment for human heal
th of chemicals in the environment are examined. Sources of uncertaint
y in the experimental approach to defining toxic hazards and risks are
described and so are factors that limit the quality of many epidemiol
ogical studies of population toxicity. It is important for the toxicol
ogist to consider all forms of risk both as probabilities and in terms
of the nature and severity of the harm done to those affected. Toxico
logy, especially in its application to man and environmental hazards,
may be influenced by societal and other politico-economic factors. Tox
icologists must take care, therefore, to be recognised as true profess
ionals, by recognising their obligations both to the proximate user of
their results and their wider responsibilities to society.