In the public's chemical residues still dominate in the ranking of foo
dborne hazards. This perception is changing slowly as a result of publ
ic discussions on the dangers to human beings from various microorgani
sms in foodstuffs. Statistics on foodborne infections and intoxication
s comprising acute diseases have shown that chemical substances (inclu
ding fungal toxins) play a less significant role than bacteria. A sent
inel and a population study from Holland provides information on the i
ncidence of cases of acute gastroenteritis caused by microorganisms in
foods. The results of this study show that 100 to 150 cases are to be
expected annually per 1000 inhabitants. An economic cost of about $ 1
000 per case of disease is calculated in Canada and the USA. On the ba
sis of these figures and the Dutch study, the estimated annual economi
c impact is more than 10 billion DM for the Federal Republic of German
y. The difficulties in quantification of microbiological hazards from
foodstuffs on the base of dose-response relation and exposure assessme
nt such as are usual in the risk assessment of chemical hazards are di
scussed. A safety concept of the food industry (the HACCP concept) is
then described, This comprises hazard identification, risk assessment
as well as risk management. This concept is also applicable in other f
ood areas such as communal catering. In the meantime, it has also been
taken into consideration in European food legislation.