THE HEPATIC TRANSPLANT PROGRAM AT THE HOS PITAL-GENERAL-UNIVERSITARIO-GREGORIO-MARANON - ANALYSIS OF THE FIRST 100 PATIENTS

During a 3 year period between 1990 and 1993, 100 patients received or thotopic liver transplantation at the <<Gregorio Maranon>> Universitar y General Hospital. The mean age of the patients was relatively high ( 46,9+/-10 years), with an important number of cirrhotic patients (91%) . The rate of primary liver failure was relatively low (4.5% of transp lantations) although 12 cases with more than 55 years were included in the present series. Eleven retransplantations were performed, 8 for e arly failure of the graft and 3 for chronic failure. postoperative com plications of the graft were vascular in 9 cases, biliary in 17 cases, and acute rejection (celular) in 70 patients, although only 50 of the se patients required treatment with steroid boluses. Infections were d iagnosed in 60 cases with 80% of major infections, 6 of them caused by Aspergillus fumigatus that were lethal in all the cases. Postoperativ e survival was 82%, 72%, 69% and 69% at 1 month, 6 months, 1 year and 2 years respectively.