We report on the management of a neonate undergoing arterial switch fo
r transposition of the great arteries and concomitant resection of a h
epatic infantile hemangioendothelioma. A preoperative aortogram demons
trated the arterial supply of the hepatic hemangioendothelioma. Pulmon
ary artery hypertension and myocardial ischemia were noted after separ
ation from cardiopulmonary bypass. Resection of the hepatic malformati
on produced an immediate reduction in pulmonary hypertension and resol
ution of the myocardial ischemia. The patient had an uneventful postop
erative recovery.